Societies can only progress from limited, natural-resource-based economies to the un-limited knowledge-based economies, once they have achieved a critical mass of innovators and entrepreneurs and a suitable environment to nourish these activities.

Mission

To help create knowledge based economies through promoting a culture of innovations and hence breaking the cycle of poverty, ignorance, disease, intolerance and all that sustains it.

Methods:
Technology falls into three broad categories:
Technology of living: from cars to clothes, Cameras to computers etc.
Technology of life: Medical technology.
Technology of death: Military technology.

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My quest is through innovations in the technology of life:

 

(And whoever saves one – it is as if he had saved mankind entirely – (Al-Quran 5:32).

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PATENTS & PROJECTS

PATENTS:

  1. Sternotomy spacing device (Q-Stent): (Sternotomy spacing device (Q-Stent): (QA/201407/00268, PCT/IB2014/002337; WO/2016/012829, EP3171788, CA2958792, AU2014401733, CN106687051, US20170215858, KR1020170047236, JP2017525527, SA517380766). Priority date 23.7.2014. Published.
  2. Electronic Chest Drain Monitor. (System, apparatus, method, and computer readable medium for monitoring volume and rate of air drained from a body): U.S. Patent No. 10,172,982, awarded on 08.01.2019. Taking priority from US Provisional Application No. 62/133,622, filed Mar. 16, 2015). GRANTED.
  3. Electrically conductive balloon. (Balloon for catheter coated with multilayer electrically conductive material and manufacturing method thereof) South Korean patent no. 10-2017-0113174. Awarded on 04.11.2019. Via Hanyang University Industry-Academic Cooperation Foundation. Application number: 10-2017-0113174, Submitted on: 24.9.2017. GRANTED
  4. An airway cardioverter-defibrillator system. (A novel cardioverter-defibrillator system using an oro-pharyngeal path). PCT/QA2017/000005. PCT International filing date 30 November 2018. In national phase.
  5. A device and method of confining and controlling bleeding during surgical operations. USPTO Patent-pending. Application number 62864747. Filed on 21.6.2019.
  6. A system & method for the detection and estimation of ventricular wall motion abnormalities. USPTO Patent-pending. Application number 62938345. Filed on 21.11.2019.
  7. An apparatus and kit for the in-vivo rib fixation via video assisted thoracic surgery and method thereof. Application number 63016635 filed on 28 April 2020.
  8. A multidimensional ventilatory circuit system derived from a single ventilator source with antimicrobial provision. Application number 63001337. Filed on 29 march 2020.
  9. Portable hyperbaric Oxygen (PHBO) hood for Covid-19 patients. Application number 63196442. Filed on 6th march 2021, by Qatar foundation to USPTO.

INTRODUCTION TO SOME OF THE INNOVATIONS

1. Dynamic Ventilatory circuit divider

A smart ventilatory divider which can safely provide ventilation to two patients or two lungs of one patient (with a novel blind double-lumen ET tube) through one ventilator. The innovation allows individual control and supply of PEEP, Flow, Pressure, FiO2 and rate to its individual recipient by a modular modification to the ventilatory circuit divider.
Winner of the AHS innovations award, June 2020.
Proof of concept Prototype completed. Pre-mass production prototype near completion.
Patent applied for.

2. A Mechatronic, bio-mimicking CPR Simulator

Winner of MRC-HMC research award.
First-of-its-kind in-vitro platform to test hundreds of possible combinations of chest compression methods, sequences, timings, rate, force and direction of force with an objective monitoring of “cardiac” output.
The system is operated by novel mathematical formulae which allow the simulator to be programmed for ALL possible combinations of existing & foreseeable, novel mechanical interventions.
Found a novel combination and method producing >60% higher cardiac output than all the existing methods.
Presented to the European resuscitation Council meeting on 16-17 July 2022 I Belgium. Most viewed presentation.
Mazhar, Rashid, et al. "P063 A mechatronic bio-mimicking simulator to study various combinations of mechanical compressions during CPR." Resuscitation 175 (2022): S56-S57.
Patent applied for.

3. Portable Hyperbaric Oxygen (PHBO) hood

A point-of-care, Artificial-intelligence-enhanced, hyperbaric Oxygen delivery system for Hypoxic patients, particularly infective patients as with COVID-19 respiratory failure. This would provide another option, before endotracheal intubation and mechanical ventilation, for treating patients with hypoxia.
Ergonomic & safe solution: enables easy patient access and ensures ongoing caregiver interaction by design, including the ability to quickly decompress the system in an emergency. It includes a smart interface that ensures personalized care by providing continuous data about patient respiratory status through a controller that leverages deep learning algorithms fine-tuned to the patient’s health status.
Winner of AHS innovation award.
Functional prototype completed. Awaiting animal studies.
Paten applied for: Application number 63196442. Filed on 6th march 2021, by Qatar foundation to USPTO.

4. Q-Stent(TM):

First mechanical surgical device developed in Qatar. A simple mechanical solution for Delayed Sternal closure in Cardiac surgery. The device is already in regular clinical use at HMC paediatric and adult cardiac surgery.

RELATED PRESENTATIONS:
  • R Mazhar. Simple device to keep the sternum open for the purposes of delayed sternal closure. (Presented at the 21st annual meeting of the Asian society for Cardiovascular and Thoracic surgery, Osaka Japan, April 4-7, 2013).
  • R Mazhar, R Lone. M Riyas, A Bhat, A Sallehudin. Delayed Sternal Closure, Initial Clinical experience of a novel device developed in Qatar. (Presented at the Qatar Foundation-Annual Research Conference, Doha, Qatar, 24-25 Nov. 2013).

5. Electronic chest Drain monitor

A real-time, precise electronic device for monitoring post-operative blood and air leak, with local and distant data display. Successfully tested in clinical setting.

  • Winner Of the Annual GCC engineering design competition Sharja – 2012.
  • Nominated for European Association of Cardio Thoracic Surgery (EACTS) Techno college award Oct. 2013.

6. Bi-manual, Screen-less ECG monitoring system.

A novel emergency ECG monitoring system which is highly portable (Size of a match-box, weighing 100 gm) and displays the rhythm on any smart phone.
The system input comes from electrodes placed on either palms or the back of two hands or wrists. It frees from the need of a specific monitor screen and training for electrode placement. Ideal for Military and out-of-hospital use.
The sensor box can also “communicate” with any conventional monitor to display its rhythm.
Prototype fabricated and human tested.

7. CPR Monitor (RM monitor).

A novel, real time, non-invasive monitor for the out-put generated by chest compressions during CPR. Present CPR quality monitoring devices are only concerned with in-put feedback (rate and depth of chest compression). Arterial lines and End Tidal CO2 is only applicable in intensive care and intubated patients, respectively.

RM monitor is the first of its type which communicates with the resuscitator, in real-time, regarding the adequacy of chest compressions.
First prototype validated, through HMC Medical research council, on human subjects.
Second prototype in the process of fabrication.
Further details withheld for IP concerns.

8. Airway Cardioverter-Defibrillator

A system for defibrillating through the Oro-pharyngeal path. Winner of 0.5 Million QR innovation competition award.
Functional prototype ready. Awaiting animal studies.
Two patents generated from the work so far.
Patent no. 10-2042450 South Korean Patent office, granted on 4.11.2019
International patent: WO 2019/108078 A1 filed 30.11.2017

9. Early ACS diagnostic monitor

Winner of 100,000 US$ innovation competition award.
Artificial-intelligence based method for point-of-care, rapid diagnosis of patients with Acute Coronary Syndrome.
Prospective clinical study proceedings underway.
Patent applied for.

10. A novel Passive restraint system for decreasing motor vehicle deceleration injuries.

A system for decreasing the incidence of Aortic rupture & other deceleration-induced injuries during car crash. In case of high speed traffic accidents, the system decreases, by 80%, the deceleration forces on the Aorta. Testing platform completed and validated. A novel computer simulation – based upon MRI anatomical as well as physiological data.

11. Enhanced VATS Platform

A bridge between Manual Video-assisted and Robotic surgery, delivering all the optical and mechanical advantages of Robotic surgery system’s at a fraction of the cost of the operating Robotic system with additional sensory and logistic advantages.

Work in progress on the proof-of-concept model.
Further details withheld for IP concerns.

12. Tracheal dilator kit.

Winner of Qatar Foundation innovation coupon award 2021. An ergonomic set of Tracheal dilators while maintaining the ventilation.
Prototype under fabrication.
Patent applied for.

13. Endoscopic (VATS) fixation system for rib fractures

A totally video-assisted method and device for fixing fractured ribs. Avoidance of external, open approach. Proof-of-concept prototype fabricated.
Patent applied for.

14. An ergonomic direct Laryngoscope

A modified direct Laryngoscope which incorporates 5 modifications to the existing designs.
Proof of concept model being fabricated.
Further details withheld for IP concerns.

AND Many more…………………………….

15. Functional Decortication

A standardised, step-by-step, function-based, minimally-invasive method for treating late-stage Empyema thoracis. The method is easily reproducible and trainable.

Mazhar R, Ashraf S. Functional decortication – an objective, minimal-access approach for late-stage empyema. 23rd annual meeting of ASCVTS Hong Kong 11-14 May, 2015.

Project Title Dates Grant Funding Agency Present Status Project outcome
Oro-Tracheal Defibrillator – a novel device to improve the outcome of CPR. 2014 0.5 Million QR 2014 Academic Health System (AHS) Innovation award. completed Patent in national phase.
Prototype
fabrication in progress
Objective monitoring of the efficacy of resuscitation, by using a novel resuscitation monitoring device (RM Monitor) 2015 0.5 Million QAR 2014 Academic Health System Innovation award. completed Prototype
fabrication in progress.
“Robotic Assistants in Operating Rooms in Qatar “Theory, Development and Integration”. Project 449-2-181, in collaboration with Purdue University, USA 11/20/2013-11/20/2015 US $1 Million. QNRF, NPRP funded Completed Successful
A novel device for fast track diagnosis of acute coronary syndrome in Emergency Department. May 2017. 365,000 QAR Academic Health System Innovation award. In progress Ongoing –
Prototype fabrication.
Development of a Wireless Smart Bio-mimetic Metal oxide/ceramic Composite Biomedical Implant for Bone Revision Surgery Retardation. June 2019-June2022 US$ 594,108 QNRF, NPRP 11S-0102-180178 In progress Ongoing
Personalized Monitoring and Advance Warning System for Cardiac Arrhythmias. June 2019-June2021 US$ 393,446 QNRF, NPRP 11S-0108-180228 In progress Ongoing
Mechatronic research simulator for CPR (a pilot project) MRC-01-19-428 Nov. 2019 91416 QAR Medical Research centre, HMC. In progress Ongoing –
Prototype fabrication.
“Dynamic Ventilatory circuit divider” June 9th, 2020 200,000 QAR Academic Health System Innovation award. In progress Ongoing –
Prototype fabrication.
“Portable Hyperbaric Oxygen (PHBO) hood for COVID-19 patients” July 22, 2020 300,000 QAR Academic Health System Innovation award. In progress Ongoing –
Prototype fabrication.
Tracheal Dilator Kit Feb. 2022 100,000 QAR Qatar Foundation Research, Development and Innovation (QFRDI) In progress Ongoing - Prototype
fabrication.

INNOVATIVE ACADEMIC PROJECTS

  1. Co-lead PI in NPRP11S-0108-180228 entitled “Personalized Monitoring and Advance Warning System for Cardiac Arrhythmias”.
  2. Co-lead PI in NPRP11S-0102-180178 “Development of a Wireless Smart Bio-mimetic Metal oxide/ceramic Composite Biomedical Implant for Bone Revision Surgery Retardation.”
  3. Lead PI in QNRF, NPRP funded project 449-2-181, in collaboration with Purdue University, USA: “Robotic Assistants in Operating Rooms in Qatar “Theory, Development and Integration”. Duration of Funding (Dates): 11/20/2013-11/20/2015. Total amount of award: US$1 Million.
  4. Co-Supervisor: Master of Science Thesis “The Mechanism of Traumatic Rupture of Aorta: Application of the Finite Element Reconstruction and Simulation“. Eng. JiFeng Nan. Nov. 2017. Department of Mechanical Convergence Engineering. Hanyang University. South Korea.
  5. A multi-disciplinary, integrated approach to “minimal-pain” surgery.
  6. Extra-pulmonary methods of Oxygenation – a comprehensive translational study.

Awards

INNOVATION AWARDS

  • Oro Tracheal defibrillator (a novel device to improve the outcome of CPR). 0.5 M QR Awarded 16.3.2014
  • CPR monitor (A novel monitoring device for objective monitoring of the efficacy of chest compressions – “RM Monitor”). 0.5 M QR awarded 13.5.2015
  • A novel device for fast track diagnosis of acute coronary syndrome in Emergency Department. 0.365 M QR awarded May 2017
  • Personalized Monitoring and Advance Warning System for Cardiac Arrhythmias. Co-PI in QNRF, NPRP 11S-0108-180228. Awarded US$ 393,446, June 2019
  • Mechatronic research simulator for CPR (a pilot project) MRC-01-19-428. MRC grant of 91416 QAR Nov.2019
  • “Dynamic ventilatory circuit divider”. Winner of AHS innovations award for 200,000 QAR, June 2020
  • “Portable Hyperbaric Oxygen (PHBO) hood for COVID-19 patients”. Winner of AHS innovations award for 300,000 QAR, July 2020

HMC STARS OF EXCELLENCE award in research

Team leader for the following projects:
  • SOE for research category 2018. A research simulator model for maximal output CPR (research simulator CPR model)”.
  • SOE for research category 2014. Q- Stent
  • SOE for research category 2015. Electronic chest drain monitor
  • SOE for research category 2016. Screen-less ECG monitor

ABOUT/CONTACTS

Dr. Rashid Mazhar (MBBS, MCPS, FCPS, FRCS-Glasg., FRCS-Edinb.)

Senior Consultant, Thoracic surgery, Hamd Hospital, Hamad Medical Corporation, Doha, Qatar.
(Hon.) Professor Thoracic Surgery, SIUT, Karachi, Pakistan.
A/P. Clinical Cardio-thoracic Surgery, Weill-Cornell Medical College Qatar.
A/P. Clinical Cardio-thoracic Surgery, Qatar Medical College, Qatar University.
Director, Advanced Life Support courses, Hamad International Training Centre, European Resuscitation Council, Qatar Chapter. Member Industrial Advisory board, Department of Electronic Engineering, Qatar University.
Rhaq@hamad.qa, rashmazhar@hotmail.com, +974-55546920